How Veloxity Streamlined PK Analysis for Faster Client Decisions
Veloxity Labs wanted a more efficient way to generate PK parameters for nonclinical studies. By using Aplos NCA, the team moved away from a manual Excel-based workflow and began delivering PK parameters such as AUC, Cmax, and Tmax alongside concentration data, often the same day. The result was a faster internal process, stronger client responsiveness, and growing demand for PK as part of Veloxity’s bioanalytical offering.
Veloxity Labs is a bioanalytical services provider supporting drug development from discovery through clinical studies. Working with organizations ranging from emerging biotech companies to large pharmaceutical firms, Veloxity helps clients generate the data and insights needed to move programs forward with confidence. The bioanalysis data generated by Veloxity is often transferred to another provider who performs PK parameter calculations. The Veloxity team decided to evaluate if they could deliver those PK parameter values more efficiently for their clients.
"Aplos NCA has made PK analysis much faster and easier for us. What used to take one to two hours can now be turned around in minutes, and we’re able to provide PK/TK parameters alongside concentration data the same day, helping clients make faster study decisions."
Before adopting Aplos NCA, PK analysis was handled through an Excel-based workflow. That process could produce the needed outputs, but it required significant manual formatting, review, and checking to ensure everything had been entered correctly. Because the Excel-based workflow was not a PK-specific solution, there was low confidence that the results were accurate or suitable for regulatory submission. The team needed a more streamlined, user-friendly approach that reduced manual effort, limited opportunities for transcription error, made outputs easier to review and use, and could provide confidence to clients that the PK results are satisfactory for regulatory submission.
Turnaround time was also a key issue. With the Excel-based workflow, a user spent 1-2 hours preparing the data and generating the results. This was followed by internal QC checks and reviews that could require several more hours. Thus PK analysis would add one or more business days to delivery of the bioanalysis results to clients. For clients making interim study decisions, that delay mattered. When dose selection or study progression depends on rapid access to PK/TK parameters, speed becomes part of the value of the service itself.
Aplos NCA offered a more automated way to generate PK parameters while making the workflow easier to navigate and easier to trust. Instead of relying on heavy reformatting and manual checking, the team could import data, select the appropriate columns and designations, and generate outputs in a format that was more legible and easier to work with.
The software also fit well into Veloxity’s reporting process. Exported data could be grouped clearly and transferred into the team’s own reporting formats, making it easier to build customer-facing reports around the parameters most relevant to each study. Aplos NCA also supported additional learning material for decision-making around which parameters to report for different routes of administration, which added practical value beyond calculation alone.
Implementation was straightforward. After initial onboarding, Aplos NCA was incorporated into Veloxity’s workflow for nonclinical PK analysis and became easy to use as part of routine study delivery. The software supported data import, parameter selection, grouping, export, and reporting in a way that aligned with the team’s existing process. In addition, all actions are 21 CFR Part 11 compliant, which would support use for both non-GLP and GLP studies.
In practice, Veloxity uses Aplos NCA to generate PK outputs and then incorporates the most relevant parameters, along with selected bioanalytical data, into its own client-ready reports. That approach gives clients the information they need in a more focused format while still benefiting from the speed and structure of the underlying software.
The most immediate impact was speed. A workflow that previously took one to two hours could now produce PK parameters in roughly 5 to 10 minutes once the analysis was set up correctly. In many cases, the full task could be completed in about 30 minutes, allowing the team to move quickly and return to other responsibilities.
That internal efficiency translated directly into client value. Veloxity began providing PK/TK parameters at the same time as concentration data, often on the same day and sometimes within hours. In one example, BA data received at around 2:00 PM was turned into completed PK/TK word report output by 3:00 PM. That kind of turnaround gives clients faster access to the information they need to make dose decisions, evaluate interim results, and plan next steps within an active study.
The faster workflow also changed how clients engaged with the service. Some customers began including PK/TK in all upcoming non-GLP studies, rather than requesting it only occasionally. One recurring client expanded work across multiple analytes and multiple nonclinical species, with seven studies already completed and several more in the queue.
Internally, PK also became a more marketable offering. What had previously been done only once or twice a year became a growing part of the business. With a platform the team could confidently use and present externally, Veloxity was able to position itself as a more responsive partner and support a faster-moving bioanalytical service model.
As PK demand continues to grow, Veloxity is positioned to make same-day or near-real-time PK reporting part of a broader client service strategy. The combination of faster output generation, client-ready reporting, and responsiveness around interim study decisions has made PK a stronger and more scalable part of the company’s offering.
Aplos NCA has helped Veloxity Labs move from a more manual PK process to a faster, more efficient workflow that better supports both the internal team and its clients. With the ability to deliver PK/TK parameters alongside concentration data, often on the same day, Veloxity has strengthened its responsiveness, improved the client experience, and expanded PK into a more valuable part of its service offering.
