User management features added

User management features for team and enterprise accounts has been added. Administrators can now add, update, and disable users for their team and enterprise accounts using the web interface or the API.

Dashboard metrics updated

The dashboard metrics were updated for team and enterprise accounts to show the allocation and available analyses for the entire team. Individual user metrics for number of completed and failed analyses are still displayed. Also updated the displayed number of available analyses to account for any analyses currently “in flight”.

Search features added

Search boxes are available on the input data, analysis history, and user management (administrators only) pages. Users can search by filename, date, meta data, username, or other aspects of the input file, analysis, or user. Results are automatically filtered to any matching information in the list. Useful for rapidly locating a previously uploaded file or previously conducted analysis.

Updated guided tours

Updated guided tours were added to multiple pages on the Aplos NCA website. Using the “Need Help?” button on the lower left of the screen, relevant guided tours for the currently visible page are shown. These tours show you how to upload data, initiate an analysis, use the data explorer, conduct a validation, download results, and more.

Increased responsiveness of website

The website is more performant when executing an analysis. The progress of each analysis is updated every 2 seconds, whether the analysis is started from the web interface, or via submission directly through the API.

Other bug fixes

Several small bug fixes resolved issues with using some text variables for grouping, listing the company name in the technical report, and generating more informative error messages on the website.

Validation added to the Aplos NCA API and Web Interface

Users can now initiate a new validation or download results of previously executed validations. The validation initiates Aplos NCA to calculate PK parameters for 6 different input datasets that are stored on a public repository. These are: (1) single dose extravascular, (2) single dose IV bolus, (3) single dose IV infusion, (4) steady-state extravascular, (5) steady-state IV bolus, and (6) steady-state IV infusion. The calculated results are compared to the known results available from that same public repository. The validation passes if all results from all 6 datasets matches the known results exactly. The validation fails if any calculate parameters are different. The validation results include both a validation report and the 6 individual analysis packages with comparisons.

Aplos NCA Web Interface page loading times improved

Webpage loading times for the input data, analysis history and validations pages have been significantly improved.

User metrics updated

User metrics on the dashboard page have been updated to reflect the number of available analyses for a user. The time required to load the metrics has been significantly improved.

Load configuration for new analysis feature updated

The button to load a previous configuration using a prior version of the Aplos NCA engine has been improved. Analyses that used columns as inputs (e.g. for dose amount) now correctly load for a new analysis.